Asymmetric Synthesis Of Pharmaceuticals And Natural

CH8404 Asymmetric Synthesis of Pharmaceuticals and Natural Products

Knowledge
• Appreciate the range of synthetic methods available to prepare enantiomerically pure molecules.
• Know the strategies and reagents required to generate and implement new stereochemical elements within target-oriented syntheses.
• Identify key problems in both small-scale academic synthesis and large scale industrial synthesis of stereochemically pure compounds.
• Identify different reaction technology equipment and summarise the key criteria to consider before using it.

Understanding
• Understand the principles and strategies of stereoselective alkene functionalization.
• Understand main principles in the use of enabling technologies and related industrial issues together with application to target molecules.
• Recognize where organocatalysis can be applied in synthesis and which strategies in this area are available.
• Explain when alternative tools and techniques may offer significant benefit to a desired reaction outcome.